Cpc - 2nd Cpc
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Resident Pathologist: Ronaldo Abueg, M.D. Pathologist: Debbie de la Fuente, M.D., F.P.S.P
Adult Male
Extremities: pale with rigor mortis changes
Lungs: External surface covered with thin fibrinopurulent material with focal areas of thickening which appears fibrous when cut
Lungs
Focal areas of necrosis and hemorrhages
Interstitial pneumonia with severe Superimposed bronchopneumonia Polymorphonuclear infiltrates
Lungs Hemorrhagic infarcts Hyphae within the blood vessels Recent organizing thrombi Septated hyphae wih mycelia
Lungs Acute Respiratory Distress Syndrome
Esophagus Focal areas of erosions mostly on distal third
Stomach: blood all over mucosal surface with focal areas of erosions, antrum severely eroded
Small Intestines
Worms in duodenum
Severe infestation of adult worms measuring 2.0 to 4.0 mm. Foreign Body giant cells around Infested crypts
Small Intestines Severe infestation of adult worms measuring 2.0 to 4.0 mm. Foreign Body giant cells around Infested crypts
Worms in jejenum
Large intestines: severe congestion with occasional ulcers and infiltrated mainly by mononuclear cells. Lymph vessels dilated causing lymphangiectasias
Spleen: normal
Liver: moderate fatty changes
Heart: occasional hypertrophy of muscle fibers with focal interstitial fibrosis
Kidneys: except for congestion, microscopic sections were normal
Adrenals: Unremarkable
Brain: areas of necrosis with histiocytic infiltrates at the region of pontine, nuclei and longitudinal fibers of the cortico-spinal and cortico-bulbar tract with small recent hemorrhages of the pons
1.MASSIVE GASTROINTESTINAL HEMORRHAGE (2 LITERS) SECONDARY TO CHRONIC ULCERATIONS, DISTAL THIRD OF ESOPHAGUS, STOMACH, SMALL AND LARGE INTESTINES
2. MASSIVE ROUNDWORM INFESTATION, DUODENUM AND JEJENUM (CAPILLARIASIS)
3. ACUTE RESPIRATORY DISTRESS SYNDROME SECONDARY TO SEVERE BRONCHOPNEUMONIA WITH PULMONARY MYCOTIC (MUCORMYCOSIS) INFECTION AND HEMORRHAGIC INFARCTS
4. RECENT SMALL HEMORRHAGES, PONS WITH AREAS OF RECENT NECROSIS AND HISTIOCYTIC INFILTRATES AT THE REGION OF PONTINE NUCLEI AND LONGITUDINAL FIBERS OF THE CORTICO-SPINAL AND CORTICO-BULBAR TRACT
Caused by the nematode Capillariasis philippinensis Transmitted via ingestion of bird-eating fresh or brackish water fish Infection has an insidious onset with nonspecific abdominal pain and diarrhea Invasive larvae cause intestinal inflammation and villus loss
Subsequent autoinfection can lead to a severe wasting syndrome – hypoproteinemia, hypoalbuminemia, hypocholesterolemia, hence the name Wasting disease
If left untreated, progressive autoinfection can lead to protein-losing enteropathy, severe malabsorption and ultimately to death from cachexia, heart failure or superinfection.
Ingestion of fish with Capillaria Chronic Steroid use Diarrhea, GIT infestation and wasting disease
Superinfection and immunosuppression
Massive GI bleeding
Fungal pneumonia, ARDS
Multiple Organ Failure DEMISE OF THE PATIENT
Adult Male
Extremities: pale with rigor mortis changes
Lungs: External surface covered with thin fibrinopurulent material with focal areas of thickening which appears fibrous when cut
Lungs
Focal areas of necrosis and hemorrhages
Interstitial pneumonia with severe Superimposed bronchopneumonia Polymorphonuclear infiltrates
Lungs Hemorrhagic infarcts Hyphae within the blood vessels Recent organizing thrombi Septated hyphae wih mycelia
Lungs Acute Respiratory Distress Syndrome
Esophagus Focal areas of erosions mostly on distal third
Stomach: blood all over mucosal surface with focal areas of erosions, antrum severely eroded
Small Intestines
Worms in duodenum
Severe infestation of adult worms measuring 2.0 to 4.0 mm. Foreign Body giant cells around Infested crypts
Small Intestines Severe infestation of adult worms measuring 2.0 to 4.0 mm. Foreign Body giant cells around Infested crypts
Worms in jejenum
Large intestines: severe congestion with occasional ulcers and infiltrated mainly by mononuclear cells. Lymph vessels dilated causing lymphangiectasias
Spleen: normal
Liver: moderate fatty changes
Heart: occasional hypertrophy of muscle fibers with focal interstitial fibrosis
Kidneys: except for congestion, microscopic sections were normal
Adrenals: Unremarkable
Brain: areas of necrosis with histiocytic infiltrates at the region of pontine, nuclei and longitudinal fibers of the cortico-spinal and cortico-bulbar tract with small recent hemorrhages of the pons
1.MASSIVE GASTROINTESTINAL HEMORRHAGE (2 LITERS) SECONDARY TO CHRONIC ULCERATIONS, DISTAL THIRD OF ESOPHAGUS, STOMACH, SMALL AND LARGE INTESTINES
2. MASSIVE ROUNDWORM INFESTATION, DUODENUM AND JEJENUM (CAPILLARIASIS)
3. ACUTE RESPIRATORY DISTRESS SYNDROME SECONDARY TO SEVERE BRONCHOPNEUMONIA WITH PULMONARY MYCOTIC (MUCORMYCOSIS) INFECTION AND HEMORRHAGIC INFARCTS
4. RECENT SMALL HEMORRHAGES, PONS WITH AREAS OF RECENT NECROSIS AND HISTIOCYTIC INFILTRATES AT THE REGION OF PONTINE NUCLEI AND LONGITUDINAL FIBERS OF THE CORTICO-SPINAL AND CORTICO-BULBAR TRACT
Caused by the nematode Capillariasis philippinensis Transmitted via ingestion of bird-eating fresh or brackish water fish Infection has an insidious onset with nonspecific abdominal pain and diarrhea Invasive larvae cause intestinal inflammation and villus loss
Subsequent autoinfection can lead to a severe wasting syndrome – hypoproteinemia, hypoalbuminemia, hypocholesterolemia, hence the name Wasting disease
If left untreated, progressive autoinfection can lead to protein-losing enteropathy, severe malabsorption and ultimately to death from cachexia, heart failure or superinfection.
Ingestion of fish with Capillaria Chronic Steroid use Diarrhea, GIT infestation and wasting disease
Superinfection and immunosuppression
Massive GI bleeding
Fungal pneumonia, ARDS
Multiple Organ Failure DEMISE OF THE PATIENT
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