Overview of surgical conditions in HIV/AIDS Ruth Obaikol
lymphadenopathy
Differentials
TB Reactive lymphadenopathy Kaposi’s sarcoma Lymphoma
pyomyositis
Currently common in age 21-40 M>F 61.3% HIV +ve. Multiple and recurrent Staph – commonest pathogen
OTHER INFECTIONS
Abscess: psoas abscess Gangrene
Kaposi’s sarcoma
epidemic disease Aggressive and extensive Age of onset M 35 F 25 M>F 4:1 Cutaneous or visceral Assoc with HHV 8
Acute onset Symmetrical LAP Early death PRESENTATION
Skin nodules Plaques Assoc. oedema
LAP Visceral lesions Combinations
Relapses are common Wide spread disease may be resistant to medication.
Ano rectal conditions
Common presentation;
Pruritus ani Anal Pain Rectal bleeding Difficulty in passing stool Faecal impaction
Ano-rectal conditions
Anal condyloma acuminata caused by HPV 6 & 11 may be hidden got by DRE Squamous cell carcinoma Anorectal KS
Fissure in ano
Can follow hard stool/ chronic diarrhea
Anal abscess
Pain, tender fluctuant swelling assoc fever
Fistula in ano
May or may not follow abscesses
Anal ulceration secondary to HSV, TB, syphilis. Hemorrhoids
MANAGEMENT
Stage I and II just like general population Stage III and IV – conservative exception; abscesses
ACUTE ABDOMEN
50% OF HIV pts develop GI manifestations. 2x the non HIV pts are admitted 8% need intrabdominal procedures
Common causes;
Cytomegalovirus colitis Intra abdominal lymphoma Atypical mycobacteria Abd TB Acalculus cholecystitis
PRESENTATION
PAIN; occurs at different sites
Right upper quadrant Epigastric +/- jaundice Right illiac fossa pain Diffuse abdominal pain
MANAGEMENT
If the diagnosis is straight forwardmanage as HIV negative patients CDC group IV
Careful conservative/ non operative management.
Vascular
Dry gangrene ass. with vasculitis
Management
Amputation
Cardiothoracic The most common complications of pulmonary tuberculosis Empyema thoracis Pericardial effusions
Pleural effusion
Zambia- 66 to 81 % of patients with TB pleural disease were HIV +ve Treatment
Thoracostomy Chest widow
Pericardial effusion
99.9% pts HIV +ve TB origin Surgery indicated in
cardiac tamponade Constrictive pericarditis
Operations
Thoracocentesis Subxiphoid pericardiectomy
Neural surgery
Intracranial mass lesions
Toxoplasmosis Brain abscess Primary CNS Lymphomas
Transplant surgery
4-7% of patients develop end stage renal failure Higher mortality on dialysis
Benefit from transplant
Pts with HIV have HBV and HCV co infection – liver failure
May benefit from liver transplant
Urology
Renal abscess 50-60% circumcised men are less likely to get HIV during heterosexual sex.
summary
The role of surgery in HIV is
Diagnostic Curative Palliative preventive