Cal Pol
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Brand Name: Calpol Generic Name: Paracetamol Indications: mild pain, fever Drug Classification: Antipyretics, non-opioid analgesics Mechanism of Action: Inhibits the synthesis of Prostaglandins that may serve as mediators of pain and fever, primarily in the CNS by inhibiting the cyclooxygenase (COX) enzyme. Prostaglandins participate in the inflammatory response, but paracetamol has no appreciable anti-inflammatory action. Dosage: Adult: 325-650 mg q 4-6 hr or 1 g 3-4 times daily or 1300 mg q 8 hrs. Children (>14 yr): 650 mg q 4 hr prn. Children (12-14 yr): 640 mg q 4 hr. Children (11 yr): 480 mg q 4 hr prn. Special Precautions: Hepatic dse/Renal dse (lower chronic doses recommended), Chronic alcohol use/abuse, malnutrition. Pregnancy Risk Category: B Adverse Reactions: GI: Hepatic Failure, Hepatotoxicity(overdose)
GU: Renal failure (high doses/chronic use) Derm: Rash, urticaria Contraindications: Previous hypersensitivity; products containing alcohol, aspartame, saccharin, sugar, or tartrazine (FDC yellow dye #5) should be avoided in patients who have hypersensitivity or intolerance to these compounds. Forms: Chewable tablets-80 mg, 160 mg; Tablets-160 mg,325mg,500 mg; Solution-80 mg/1.66 ml, 100 mg/ml; Liquid-160 mg/5 ml, 500 mg/15 ml; Syrup-16 mg/ml. Nursing Responsibilities: Assess overall health status and alcohol usage before administering. Assess amount, frequency, and type of drugs taken in patients selfmedicating. Pain:Assess type, location, and intensity prior to and 30-60 min following administration. Fever: Assess fever; note for presence of associated signs (diaphoresis, tachycardia, and malaise). Administer with a full glass of water. May be taken with food or on an empty stomach.
GU: Renal failure (high doses/chronic use) Derm: Rash, urticaria Contraindications: Previous hypersensitivity; products containing alcohol, aspartame, saccharin, sugar, or tartrazine (FDC yellow dye #5) should be avoided in patients who have hypersensitivity or intolerance to these compounds. Forms: Chewable tablets-80 mg, 160 mg; Tablets-160 mg,325mg,500 mg; Solution-80 mg/1.66 ml, 100 mg/ml; Liquid-160 mg/5 ml, 500 mg/15 ml; Syrup-16 mg/ml. Nursing Responsibilities: Assess overall health status and alcohol usage before administering. Assess amount, frequency, and type of drugs taken in patients selfmedicating. Pain:Assess type, location, and intensity prior to and 30-60 min following administration. Fever: Assess fever; note for presence of associated signs (diaphoresis, tachycardia, and malaise). Administer with a full glass of water. May be taken with food or on an empty stomach.
