Blood Coagulation
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BLOOD
COAGULATION
When any blood vessel is damaged blood escapes and after a few minutes the blood flow stops as it thickens and forms a clot. This process is called coagulation or clotting of blood. Different events in blood coagulation are: THROMBOPLASTIN ( FROM TISSUE AND PLATELETS) PROTHROMBIN
THROMBIN CALCIUM IONS (IN PLASMA) FIBRINOGEN
The various factors responsible for blood coagulation are: I FIBRINOGEN. II PROTHROMBIN. III THROMBOPLASTIN. IV CALCIUM. V ACCELERATOR GLOBIN. VII STABLE FACTOR. VIII ANTIHAEMOPHILIAC FACTOR. IX CHRISTMAS FACTOR. X STUART- POWER FACTOR. XI PLASMA THROMBOPLASTIN ANTECEDENT. XII HAGEMAN FACTOR. XIII FIBRIN STABILISING FACTOR. NOTE: THERE IS NO FACTOR VI. ANTICOAGULANTS A. NATURAL z HEPARIN
FIBRIN(CLOT)
ANTI THROMBIN z PROTEIN C B. SYNTHETIC z VITAMIN K ANTAGONISTS eg. Dicoumarol. z CALCIUM CHELATORS like EDTA, remove calcium from blood and maintain the fluid state of blood. z
COAGULATION
When any blood vessel is damaged blood escapes and after a few minutes the blood flow stops as it thickens and forms a clot. This process is called coagulation or clotting of blood. Different events in blood coagulation are: THROMBOPLASTIN ( FROM TISSUE AND PLATELETS) PROTHROMBIN
THROMBIN CALCIUM IONS (IN PLASMA) FIBRINOGEN
The various factors responsible for blood coagulation are: I FIBRINOGEN. II PROTHROMBIN. III THROMBOPLASTIN. IV CALCIUM. V ACCELERATOR GLOBIN. VII STABLE FACTOR. VIII ANTIHAEMOPHILIAC FACTOR. IX CHRISTMAS FACTOR. X STUART- POWER FACTOR. XI PLASMA THROMBOPLASTIN ANTECEDENT. XII HAGEMAN FACTOR. XIII FIBRIN STABILISING FACTOR. NOTE: THERE IS NO FACTOR VI. ANTICOAGULANTS A. NATURAL z HEPARIN
FIBRIN(CLOT)
ANTI THROMBIN z PROTEIN C B. SYNTHETIC z VITAMIN K ANTAGONISTS eg. Dicoumarol. z CALCIUM CHELATORS like EDTA, remove calcium from blood and maintain the fluid state of blood. z
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