Biochem 322-final 2005

(B. Sc. Biochemistry) Sixth Semester 2005 Subject: Biochem 322 (Microbiol Biochemistry)

Full Marks: 100 Pass Marks: 45 Time: 3 hours

Candidates are required to give their answers in their own words as far as practicable. The figure in the margin indicates full marks. Group (A) Long Questions (Any three)

(3× ×14 = 42)

1. Describe the mechanism of resistance offered by S. aureus against vancomycin. 2. Describe the penicillin and cephalosporin biosynthetic pathway in filamentous fungi. Point out key regulatory steps. 3. Briefly give an overview on the general steps in isolation and identification of pathogens during laboratory diagnosis. 4. Explain commensalisms in detail with appropriate examples. Group (B) Short Questions: (Any six) 1. Describe the recent highlights and remaining gaps in bacterial FA-metabolism. 2. Describe the bacterial phospholipid biosynthetic pathways. 3. Describe industrial applications of Aspergillus enzymes. 4. How do thermophilic fungi maintain homeoviscous adaptation? 5. Discuss the non-cultural methods of examination of pathogens during diagnosis. 6. Describe different sources responsible for the spread of infection. 7. Describe how aerial plant structures can participate in N2-fixation. 8. Write few examples in which synergism type of interaction is possible.

(6× ×7 = 42)

Group (C) Write short notes on: (Any eight) 1. Define hVISA. 2. Discuss the importance of bacterial membrane phosphatidyl glycerol. 3. How does cerulenin act on KAS-system? 4. Define pcb AB. 5. Describe the significance of synergy between polysaccharide degrading enzymes. 6. Discuss the importance of thermophilic fungi from research point of view. 7. Define MRSA. 8. What is Meningitis? Give any four bacteria responsible for meningitis. 9. Define chemotherapy. 10. Write short notes on plant viruses. 11. Define syntrophism. 12. Why Agrobacterium tumefaciens is important from agricultural point of view?

(2× ×8 = 16)

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