Acc 2009

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Jupiter

Jupiter Tromboembolismo venoso 1,9 anos de follow-up Rosuvastatina = 34 Placebo = 60 RR = 0,61 Embolia pulmonar RR= 0,71

JUPITER

“O efeito colateral da rosuvastatina é a redução do LDL colesterol”.

Total Cost

PROTECT AF Late –Breaking Clinical Trial Percutaneous LAA closure vs Warfaring to prevent stroke in patientes with AF

Fatos sobre anticoagulação • 50 % dos pacientes com FA são elegíveis para anticoagulação. • 60 % dos pacientes em anticoagulação estão adequados. • 29% com INR abaixo • 15% com INR acima

WATCHMAN LAA

• Device 463 pacientes • Control 244 pacientes • Warfarin por 45 dias e depois parar (87% conseguiu parar). • ECO transesofágico aos 45 dias

Conclusões • 87% dos pacientes descontinuaram Anticoagulação • AVCI e morte igual • AVC Hemorrágico menos frequente. • Complicação – derrame pericárdico.

Relative Risks for Various Subgroups, According to Treatment Group

The ACTIVE Investigators. N Engl J Med 2009;10.1056/NEJMoa0901301

Great Debates in Hypertension

1. O objetivo do tratamento: Controlar a PA? Reduzir a Hipertrofia Ventricular?

Hipertrofia Ventricular: Remodelamento vascular Apoptose Fibrose – Stiffness Fibrose perivascular

Insuficiência Cardíaca Diastólica: O que fazer?

Tratar a Hipertensão! Tratar as comorbidades.

Abstracts: 24-hour Nurse telephone service improves clinical outcome in patients with chronic heart failure 181 pacientes 1 ano seguimento 45 40 35 30 25 20 15 10 5 0

41,6

Nurse Control

14

12,2

14,4 9,1

1,1 Morte

Readmissão

Custos

Zhang et al. Beijing China

Abstracts: Heart Failure Decompensation Accounts for only a minority of Readmissions in Patients Hospitalized for Heart Failure. 501.234 Altas 30 dias

% 60

52,7

50 40

25 21 20

17

35,8 15

17 13

30 10

20

11,5

10

5

0

0

ICC

Outras cardíacas

Não Cardíaca

Infecção

IRA

Respiratório

Vascular

24% readmitido em 30 dias (7 a 21 dias) Bueno et al. Yale Medical School

Abstracts: Large and Small Artery Elasticity, but not Coronary Calcium /Score and Carotid intima-meida thickness predict Incident Congestive Heart Failure Events. MESA – 6177 pacientes Abstracts: Blood Pressure Parameters, Aterial Stiffness, and Incident Heart Failure in the Elderly – The Health ABC Study- 2550 pacientes PWV Pressão de pulso

Emory University

Abstracts: Appropriateness Criteria for ECO

Abstracts: Appropriateness Criteria for Computed Tomography

D2B: An Alliance for Quality A Guidelines Applied in Practice (GAP) Program

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