Systemic Inflammatory Response Syndrome (sirs) Prognosis
This document was uploaded by user and they confirmed that they have the permission to share it. If you are author or own the copyright of this book, please report to us by using this DMCA report form. Report DMCA
Overview
Download & View Systemic Inflammatory Response Syndrome (sirs) Prognosis as PDF for free.
More details
- Words: 619
- Pages: 16
Systemic Inflammatory Response Syndrome(SIRS) Prognosis
www.ipgdx.com
Phase Angle a Prognostic Factor for Survival in SIRS
Systemic Inflammatory Response Syndrome (SIRS) is an inflammatory state affecting the whole body, frequently in response to infection.
www.ipgdx.com
Phase Angle a Prognostic Factor for Survival in SIRS
SIRS is nonspecific and not always related to infection. It is related to Sepsis,a condition in which individuals both meet criteria for SIRS and have a known or highly suspected infection.
INFECTION
SEPSIS
SIRS
www.ipgdx.com
Phase Angle a Prognostic Factor for Survival in SIRS
SIRS is defined as 2 or more of the following variables: Fever of more than 38°C or less than 36°C Heart rate of more than 90 beats per minute Respiratory rate of more than 20 breaths per minute or a PaCO2 level of less than 32 mm Hg Abnormal white blood cell count (>12,000/µL or <4,000/µL or >10% bands)
www.ipgdx.com
Phase Angle a Prognostic Factor for Survival in SIRS Burns Trauma
Infection
Irradiation ??
SIRS Pancreatitis
Bacteraemia
SIRS is one of several conditions related to systemic inflammation, organ dysfunction, and organ failure. www.ipgdx.com
Phase Angle a Prognostic Factor for Survival in SIRS
Platelets
Endothelial cells
Complement
Leucocytes
Plasmatic hemocoagulation system
www.ipgdx.com
Phase Angle a Prognostic Factor for Survival in SIRS
Causes: The causes of SIRS are broadly classified as infectious or noninfectious. When SIRS is due to an infection, it is considered sepsis. Noninfectious causes of SIRS include trauma, burns, pancreatitis, ischemia and haemorrhage. www.ipgdx.com
Phase Angle a Prognostic Factor for Survival in SIRS
Septic shock is severe sepsis with hypo tension (systolic BP < 90mmHg) despite adequate fluid resuscitation or the requirement for vasopressors/inotropes to maintain blood pressure.
www.ipgdx.com
Phase Angle a Prognostic Factor for Survival in SIRS
Here is an excerpt of the clinical observation study from 23rd International Symposium on Intensive Care and Emergency Medicine. It was concluded from the study that phase Angle acts as a predictor for survival in patients with SIRS.
www.ipgdx.com
Phase Angle a Prognostic Factor for Survival in SIRS
PrognostiCheck® for prognosis based upon a noninvasive diagnostic test measures the resistance,reactance and phase angle (in degrees).A low phase angle has been associated with an altered cellular membrane function.
www.ipgdx.com
Phase Angle a Prognostic Factor for Survival in SIRS
Tests were conducted on 30 consecutive patients( 11 female, 19 male ,median age of 67 [ 16.5 ] years ) after admitting them to the intensive care unit ,all of whom met 2 or more SIRS Criteria.
www.ipgdx.com
Phase Angle a Prognostic Factor for Survival in SIRS
In Septic shock patients,a phase angle of less than 4 degree has been reported to be associated with increases mortality. Severity of the illness was characterized according to APACHE II(Acute Physiology and Chronis Health Evaluation)
www.ipgdx.com
Phase Angle a Prognostic Factor for Survival in SIRS
Non-invasive impedance analysis was performed using a tetra-polar hand-to-foot measuring device and derived phase angle was calculated as arc tan (reactance/resistance). increasing Reactance (
)
www.ipgdx.com
Phase Angle a Prognostic Factor for Survival in SIRS
All measurements were performed in the supine position of the patient with special care. After 28 days, out of the 30 patients investigated, 10 had died and 20 survived. In seven out of 20 survivors,a phase angle of more than 4 degree was measured on the first day study,whereas in all patients who died,the phase angle was less than 4 degree (P=0.038) www.ipgdx.com
Phase Angle a Prognostic Factor for Survival in SIRS
The conclusion was that an initial phase angle of more than 4 degree may be correlated with survival,in patients suffering with SIRS.
www.ipgdx.com
PrognostiCheck
R
For more information or inquiries regarding direct investments, collaborative product development and partnerships please contact below.
By IPGDx, LLC
www.ipgdx.com [email protected] [email protected]
www.ipgdx.com
Phase Angle a Prognostic Factor for Survival in SIRS
Systemic Inflammatory Response Syndrome (SIRS) is an inflammatory state affecting the whole body, frequently in response to infection.
www.ipgdx.com
Phase Angle a Prognostic Factor for Survival in SIRS
SIRS is nonspecific and not always related to infection. It is related to Sepsis,a condition in which individuals both meet criteria for SIRS and have a known or highly suspected infection.
INFECTION
SEPSIS
SIRS
www.ipgdx.com
Phase Angle a Prognostic Factor for Survival in SIRS
SIRS is defined as 2 or more of the following variables: Fever of more than 38°C or less than 36°C Heart rate of more than 90 beats per minute Respiratory rate of more than 20 breaths per minute or a PaCO2 level of less than 32 mm Hg Abnormal white blood cell count (>12,000/µL or <4,000/µL or >10% bands)
www.ipgdx.com
Phase Angle a Prognostic Factor for Survival in SIRS Burns Trauma
Infection
Irradiation ??
SIRS Pancreatitis
Bacteraemia
SIRS is one of several conditions related to systemic inflammation, organ dysfunction, and organ failure. www.ipgdx.com
Phase Angle a Prognostic Factor for Survival in SIRS
Platelets
Endothelial cells
Complement
Leucocytes
Plasmatic hemocoagulation system
www.ipgdx.com
Phase Angle a Prognostic Factor for Survival in SIRS
Causes: The causes of SIRS are broadly classified as infectious or noninfectious. When SIRS is due to an infection, it is considered sepsis. Noninfectious causes of SIRS include trauma, burns, pancreatitis, ischemia and haemorrhage. www.ipgdx.com
Phase Angle a Prognostic Factor for Survival in SIRS
Septic shock is severe sepsis with hypo tension (systolic BP < 90mmHg) despite adequate fluid resuscitation or the requirement for vasopressors/inotropes to maintain blood pressure.
www.ipgdx.com
Phase Angle a Prognostic Factor for Survival in SIRS
Here is an excerpt of the clinical observation study from 23rd International Symposium on Intensive Care and Emergency Medicine. It was concluded from the study that phase Angle acts as a predictor for survival in patients with SIRS.
www.ipgdx.com
Phase Angle a Prognostic Factor for Survival in SIRS
PrognostiCheck® for prognosis based upon a noninvasive diagnostic test measures the resistance,reactance and phase angle (in degrees).A low phase angle has been associated with an altered cellular membrane function.
www.ipgdx.com
Phase Angle a Prognostic Factor for Survival in SIRS
Tests were conducted on 30 consecutive patients( 11 female, 19 male ,median age of 67 [ 16.5 ] years ) after admitting them to the intensive care unit ,all of whom met 2 or more SIRS Criteria.
www.ipgdx.com
Phase Angle a Prognostic Factor for Survival in SIRS
In Septic shock patients,a phase angle of less than 4 degree has been reported to be associated with increases mortality. Severity of the illness was characterized according to APACHE II(Acute Physiology and Chronis Health Evaluation)
www.ipgdx.com
Phase Angle a Prognostic Factor for Survival in SIRS
Non-invasive impedance analysis was performed using a tetra-polar hand-to-foot measuring device and derived phase angle was calculated as arc tan (reactance/resistance). increasing Reactance (
)
www.ipgdx.com
Phase Angle a Prognostic Factor for Survival in SIRS
All measurements were performed in the supine position of the patient with special care. After 28 days, out of the 30 patients investigated, 10 had died and 20 survived. In seven out of 20 survivors,a phase angle of more than 4 degree was measured on the first day study,whereas in all patients who died,the phase angle was less than 4 degree (P=0.038) www.ipgdx.com
Phase Angle a Prognostic Factor for Survival in SIRS
The conclusion was that an initial phase angle of more than 4 degree may be correlated with survival,in patients suffering with SIRS.
www.ipgdx.com
PrognostiCheck
R
For more information or inquiries regarding direct investments, collaborative product development and partnerships please contact below.
By IPGDx, LLC
www.ipgdx.com [email protected] [email protected]
Related Documents
Patho-inflammatory Response
May 2020 19
Prognosis
June 2020 31
Systemic Inflammatory Mediators And Cystic Fibrosis Genotype
November 2019 7
Inflammatory Disorders
November 2019 9More Documents from ""
Breast Cancer Prognosis
June 2020 16
Lung Cancer Prognosis
June 2020 23
Food Safety
May 2020 26