Stem Cell Procedure- Spinal Cord Injury Treatment

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"CLEAN BREAK SCI"  At least one year post­lesion; max ten years, Asia A or B only Pickup at Lisbon (or Athens) airport with van.

Surgical Procedure Surgical intervention is performed under general anesthesia with endotracheal intubation. The patient is positioned in park bench– like position. The surgical procedure is performed in 3 steps. In the first step, the neurosurgeons exposed the damaged spinal cord by a standard midline incision, posterior laminectomy, and opening of the dura mater. The damaged spinal cord is approached by a posterior midline myelotomy. Then scar tissue of the lesion is removed (within limits as to not harm normal cord tissue) to expose the gross viable nervous tissue in both stumps. The surgical wound is temporarily closed. The second step is performed by the otolaryngologists. To harvest the olfactory mucosa graft, a transnasal endoscopic approach and instrumentation are used A submucoperiosteal tunnel is created in the most posterior–superior region of the medial (septal) side of the olfactory groove, and sufficient tissue is collected to fill the spinal cord cavity and to allow for histological and microbiological examination. Reabsorbable packing is placed in the olfactory groove to avoid postoperative nasal bleeding. The last step involved the transplantation of the olfactory mucosa into the SCI site. Before implantation, the graft is immersed in cerebro-spinal fluid (CSF) and cut into small pieces with the surgical microscope, to increase the surface area of the grafted tissue. Meninges and the superficial tissue layers are sutured into place. Wound clips are used to close the skin. The patients are

transferred to the surgical intensive care unit postoperatively. Transport to airport for return home in one week.

 

Start rehab around 3 weeks after surgery

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