Presbyopia Correction for Middle Aged High Myopia
Case of High Myopia Patient F/47 HOO 2008.4.15. First visit CC) Far & Near vision disturbance MR OD : -12.0sph
OS : -7.25sph = -1.5cyl A135 Add : +1.5D (OU)
1) 2008.9.2/9.4
OD) +10D Alcon IQ IOL insertion OS) +13.5D Alcon IQ IOL POD #2M
UCVA Far : FC/0.04 Near : J16/J16 BCVA
Far : 0.5/0.7 Near : J5(0.333)/J7(0.287)
2nd Step : Keralaser presbyopia correction
MR(OD) UCVA(OD) BCVA(OD)
2) 2008.11.19 POD #1D
Surgical Plan (OU): 1st Step : Cataract operation
Phaco with IOL (OU)
-2.25D sph. Far : 0.3 Near : J1 (0.8) Far : 0.8 Near : J1+(1.0)
Keralaser (OD)
UCVA(OD)
Far : 0.8 Near : J1+ (1.0)
Kera Pesbyopia #1D
Phaco+IOL #2M
Short Term Result of Presbyopia Correction Using Kera Laser
Method & Patients
Prospective clinical trial ▪ Period : 03. 2008 ~ 10. 2008 by Park Woo Chan ▪ Group : 40 Eyes * Myopic Presbyopia (24 eyes) (PRK:LASIK = 13:11) * Hyperopic Presbyopia (16 eyes) (PRK:LASIK = 0:16) Follow up: 1 주일 , 2 주일 ,1 개월 , 2 개월 , 3 개월 , 6 개월
Pre& postoperative examinations • • • • • • • • • • • • •
UCVA (Far & Near) BCVA (Far & Near) AR, MR, Wavefront refraction Slit lamp examination Keratometer Topography Pachymeter Pupillometer Specular microscopy BUT, Schirmer test Corneal sense by Cochet-Bonnet aesthesiometer IOP, VF, OCT Contrast sensitivity (CSV-1000) mesopic, photopic & halogen • Wavefront Aberration Analysis (LadarWave) • Fundus examination
Method • 수술은 한 명의 술자 (Park Woo Chan) 에 의해 시행 • PRK 군은 모두 띠모양 양막과 T-lens 사용함 . • LASIK 군은 Hansatome® 을 이용해 160 ㎛의 각막절편 • • 통계 분석은 SPSS(release 12.0K) 의 T-test 와 , 상관관계 를 알아보기 위해 피어슨 상관계수 (Pearson correlation coefficient) 를 이용하였고 , P<0.05 를 통계학적으로 유의하 다 하였다 .
Demography Eyes Male/Femal e (eyes)
Age
Mean F/U period (month)
Myopic Presbyopia
24
3/21
51.25 ± 3.18
4.17 ± 1.74
Hyperopic Presbyopia
16
6/10
53.88 ± 4.86
2.50 ± 1.71
Total
40
9/31
52.30 ± 4.09
3.50 ± 1.89 (range: 1~7 month)
Biometry Myopic Presbyopia (24 eyes)
Hyperopic Presbyopia (16 eyes)
Total (40 eyes)
Pupil Size (mm)
6.50 ± 0.79
5.53 ± 0.64
6.11 ± 0.87
Central CT (um)
574.67 ± 24.10
552.56 ± 29.10
565.83 ± 28.08
2350.71 ± 414.88
2467.38 ± 347.01
2397.38 ± 388.81
14.46 ± 2.47
16.13 ± 2.78
15.13 ± 2.69
Schirmer Test (mm)
6.13 ± 5.19
8.00 ± 6.25
6.88 ± 5.63
BUT (sec)
5.59 ± 2.94
6.29 ± 2.97
5.86 ± 2.93
Corneal Sense (cm)
5.44 ± 0.53
5.50 ± 0.58
5.42 ± 0.52
Preop. SE (D)
-2.86 ± 1.87 (-0.125 ~ -6.125)
0.84 ± 0.50 (0 ~ +1.75)
Endothelial CD IOP (mmHg)
CT = Corneal Thickness,
CD = Cell Density, SE = spherical equivalent
Results
PRK vs LASIK in Myopic Presbyopia
J1 J1+ J1 J2 J3 J5 J10 J16
J3 J5 J10
PRK vs LASIK in Myopic Presbyopia (D)
Change of Visual Acuity 근시성 노안 (Far)
근시성 노안 (Near)
1. 2
1. 2
1. 0
1. 0
0. 8
0. 8
0. 6
0. 6
0. 4
J1+ J1 J2 J3 J5 J10 BCVA(N)
0. 4 BCVA(F)
0. 2
UCVA(F)
0. 0
0. 2
UCVA(N) J16
0. 0 술전
1주
2주
1개월
2개월
3개월
6개월
술전
1. 2
1. 2
1. 0
1. 0
0. 8
0. 8
0. 6
0. 6 BCVA(F)
0. 2
UCVA(F)
0. 0 술전
1주
2주
1개월
2개월
2주
1개월
2개월
3개월
6개월
원 시성 노 안 (Near)
원 시 성 노안 (Far)
0. 4
1주
3개월
J1+ J1 J2 J3 J5 BCVA(N)J10 J16 UCVA(N)
0. 4 0. 2 0. 0 술전
1주
2주
1개월
2개월
3개월
Gain & Loss of Visual Acuity
Eye
POD : 3mo
Cumulative UCVA (%)
근시 노안 (Far)
(%)
근시 노안 (Near)
J1+
(%)
원시 노안 (Far)
J1+~J2
J2~J3
J3
원시 노안 (Near)
(%)
J1+
J1+~J2
J2~J3
J3
Change of Spherical Equivalent 근시 노안
(D) 0. 5 0. 0 - 0. 5 - 1. 0 - 1. 5 - 2. 0 - 2. 5 - 3. 0 - 3. 5 술전
1주
2주
1개월
2개월
3개월
6개월
원시 노안
(D) 1. 0 0. 8 0. 6 0. 4 0. 2 0. 0 - 0. 2 - 0. 4 - 0. 6 - 0. 8 술전
1주
2주
1개월
2개월
3개월
Achieved vs Attempt Correction (D)
(D)
(D)
(D)
Pearson 상관계수 : 0.890, P=0.000 ≤ ± 0.5 D : 55.00% (n=20) ≤ ± 1.0 D : 57.45%
Pearson 상관계수 : 0.493, P=0.104 ≤ ± 0.5 D : 83.33% (n=12) ≤ ± 1.0 D : 91.67%
POD : 3mo
Change of High Order Aberration (6 mm OZ)
(um)
(um)
Change of Contrast Sensitivity Photopic
Mesopi c
Haloge n
3 cpd
6 cpd
12 cpd
18 cpd
3 cpd
6 cpd
12 cpd
18 cpd
3 cpd
6 cpd
12 cpd
18 cpd
근시
술전
5.04
4.79
4.67
4.46
5.00
4.79
4.21
4.13
4.92
4.92
4.04
4.54
노안
1 개월
4.94
4.39
3.78
4.00
4.78
4.72
3.94
4.06
4.61
4.33
3.89
4.11
2 개월
5.31
5.15
4.92
4.54
5.23
5.15
5.00
4.46
4.92
4.69
4.85
5.00
3 개월
5.00
4.82
5.00
4.18
5.18
4.82
4.64
4.27
5.09
4.91
4.64
4.00
6 개월
5.50
5.00
5.00
4.75
5.63
4.88
5.13
4.75
5.50
4.88
4.75
4.63
3 cpd
6 cpd
12 cpd
18 cpd
3 cpd
6 cpd
12 cpd
18 cpd
3 cpd
6 cpd
12 cpd
18 cpd
원시
술전
5.00
5.19
5.25
5.13
5.13
5.06
4.75
5.00
5.00
4.94
4.75
5.13
노안
1 개월
5.10
5.30
4.70
4.90
5.00
5.20
4.60
4.90
5.10
4.70
4.30
5.00
2 개월
5.00
5.50
4.50
5.50
4.00
5.50
4.75
4.25
5.00
5.25
4.25
5.00
3 개월
5.00
5.50
5.00
5.50
5.00
5.00
5.00
5.50
5.00
5.00
5.00
5.00
6
근시 노안
5 4 3 2
Photopic
1 0 3 cpd
6 cpd
12 cpd
18 cpd
6 5 4 3 2
Mesopic
1 0 3 cpd
6 cpd
12 cpd
18 cpd
6 5 4 3 2
Halogen Glare
1 0 3 cpd
6 cpd
12 cpd
18 cpd
6
원시 노안
5 4 3 2
Photopic
1 0 3 cpd
6 cpd
12 cpd
18 cpd
6 5 4 3 2
Mesopic
1 0 3 cpd
6 cpd
12 cpd
18 cpd
6 5 4 3 2
Halogen Glare
1 0 3 cpd
6 cpd
12 cpd
18 cpd
Change of other factors
Change of other factors PRK
LASIK