اخبار پژوهشگاه دانش هاي بنيادي - Ipm
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http://www.ams.org/mrcitations/search.html
2 L. CALZA and S. GARBISA, Italian professorships, Nature 374 (1995), 492.
5. Leeds University, http://www.leeds.ac.uk/library/teams/rae
3 J. Goldberg, Why web usage statistics are (worse than) meaningless, (http://www.goldmark.org/netrants/webstats/ : Last accessed June 2006).
6. Kings College, London, http://www.kc1.ac.uk/research/rae/
4 R. Monastersky, The number that's devouring science, The Chronicle of Higher Education, 2005, (http://chronicle.com/weekly/v52/i08/08a01201.htm: Last accessed June 2006). 5 V. Milman, Impact factor and how it relates to quality of journals, Notices of AMS 53 (2006), 351-352. (http://www.ams.org/notices/ 200603/ comm-milman.pdf : Last accessed June 2006).
4. University of Edinburgh, Research Assessment Exercise 2008, Outputs, http://www.inf.ed.ac.uk/admin/rae/outputs.html
notes.html
7. RAE 2008 Guidelines, p. 22, http://www.rae.ac.uk/pubs/2005/03 =
7 P.O. SEGLEN, Why the impact factor of journals should not be used for evaluating research, BMJ 314 (1997), (http://bmj.bmjjournals.com/cgi/ content/full/314/7079/497: Last accessed June 2006).
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http://www.ams.org/mrcitations/search.html
2 L. CALZA and S. GARBISA, Italian professorships, Nature 374 (1995), 492.
5. Leeds University, http://www.leeds.ac.uk/library/teams/rae
3 J. Goldberg, Why web usage statistics are (worse than) meaningless, (http://www.goldmark.org/netrants/webstats/ : Last accessed June 2006).
6. Kings College, London, http://www.kc1.ac.uk/research/rae/
4 R. Monastersky, The number that's devouring science, The Chronicle of Higher Education, 2005, (http://chronicle.com/weekly/v52/i08/08a01201.htm: Last accessed June 2006). 5 V. Milman, Impact factor and how it relates to quality of journals, Notices of AMS 53 (2006), 351-352. (http://www.ams.org/notices/ 200603/ comm-milman.pdf : Last accessed June 2006).
4. University of Edinburgh, Research Assessment Exercise 2008, Outputs, http://www.inf.ed.ac.uk/admin/rae/outputs.html
notes.html
7. RAE 2008 Guidelines, p. 22, http://www.rae.ac.uk/pubs/2005/03 =
7 P.O. SEGLEN, Why the impact factor of journals should not be used for evaluating research, BMJ 314 (1997), (http://bmj.bmjjournals.com/cgi/ content/full/314/7079/497: Last accessed June 2006).
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