Pathway Kmb 2.docx

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PATHWAY HIPERSENSITIVITAS

IgE spesifik terhadap zat alergen

Debu, tungau, bulu binatang peliharaan

Protein : susu sapi, telur, ikan laut

Obat-obatan

Zat allergen masuk ke dalam tubuh

Allergen menempel pada sel mast

Sel-sel reseptor Igw (sel mast, basophil, eusinofil) mengikat IgE

Sel mast mengalami degranulasi (pecah)

Degranulasi mengeluarkan berbagai mediator kimia

Histamine, Bradikinin, Prostaglandin

Gejala hipersensitivitas/ Alergi

Respiratorius

Integumen

Inflamasi/ alergi saluran nafas

Reaksi alergi

Udema laring,bronkospasme

Masuk ke pembuluh darah perifer

Asma brorkial Urtikaria, pruritus MK : Gangguan pola nafas MK : Gangguan integritas kulit

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