Overcoming Infectious Disease

1800 – Continuity or Change? • • • •

Continuity Still don’t understand cause of disease Quacks Problems in surgery – infection, pain, bleeding Rapid industrialization meant worse public health

• • • • • •

Change Technology, especially microscope (1683) Chemistry – gases Doctors better trained, closer observation Surgeons better trained via colleges Dissection, better understanding, new surgical procedures Vaccines, first in 1798

From the 19th to the 20th Century many people battled to overcome Infectious disease. The most important are below and their work should been seen as complimentary to each other:Jenner (smallpox vaccine) + Pasteur (germ theory, vaccines) + Koch (proved germs caused disease, bacteriology) + Behring (anti-toxins) + Ehrlich (first chemical drug, Salvarsan 606) + Domagk (Prontosil, Sulphonamides) FLEMING, FLOREY AND CHAIN, PENICILLIN to ANTIBIOTICS