Mendelian Basis of Inheritance
Gregor Mendel- Father of Genetics
Studies of Gregor Mendel
Mendel’s 4 Postulates Unit factors in pairs Dominance /Recessiveness Segregation Independent Assortment
Monohybrid Cross
Monohybrid Cross Genotype-genetic
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makeup of an individual Phenotype-physical traits of an individual as expressed from the genotype
Testcross
Problem Solving:
1. In a cross between a black and a white guinea pig, all members of the F1 generation are black. The F2 generation is made up of ¾ black and ¼ white guinea pigs. Diagram this cross, showing the genotypes and phenotypes. 2. Albinism in humans is inherited as a simple recessive trait. For the ff families, determine the genotypes of parents and offspring. When two alternative genotypes are possible, list both. A. Two normal parents have five children, four normal and one albino. B. A normal male and an albino female have six children, all normal. C. Which of the Mendel’s postulates are illustrated?
Dihybrid Cross
Problem Solving: Mendel crossed peas having round seeds and yellow
cotyledons with peas having wrinkled seeds and green cotyledons. All the F1 plants had round seeds with yellow cotyledons. Diagram this cross through the F2 generation using both the Punnett square or branch method. With regard to the ABO blood types in humans, determine the genotypes of the male parent and female parent: Male Parent: Blood type B whose mother was type O Female Parent: Blood type A whose father was type B. Predict the blood types of the offspring that this couple may have and the expected proportion of each.
Principle of Segregation
Incomplete Dominance
Multiple Allelism Dominance/Recessiveness Codominance
Epistasis
Trihybrid Cross
Human Inheritance