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DIPOLOG MEDICAL CENTER COLLEGE FOUNDATION ALLIED MEDICAL SCIENCES MEDICAL TECHNOLOGY DEPARTMENT FIRST SEMESTER SY 2018-2019

PERIOD August 13 – 20, 2018 TOPIC : Liver Function Test A. Gross and Micrsocopic anatomy of Liver B. Functions of liver I. Synthetic Function and its corresponding Laboratory test a) Total protein b) Albumin c) A/G ratio II. Conjugation and Excretion Function and its corresponding Laboratory test a) Bilirubin metabolism and disorders b) Bilirubin assay c) Bromsulfonthalein (BSP) Dye excretion Test III. Detoxification Function a) Enzyme tests b) Ammonia Powerpoint Presentation Quiz Difference between Nephrotic and Nephritic Syndrome Chapter Exam Advance reading for Enzymes

DIPOLOG MEDICAL CENTER COLLEGE FOUNDATION ALLIED MEDICAL SCIENCES MEDICAL TECHNOLOGY DEPARTMENT FIRST SEMESTER SY 2018-2019

PERIOD TOPIC : ENZYMES A. Introduction to Enzymes I. Nomenclature of enzymes II. Classification of enzymes III. Identification of terms related to enzymes IV. Mode of Enzyme Activity V. Models for enzyme activity a) Lock and Key model (Emil Fisher) b) Induce fit model (Daniel Koshland) VI. Factors Affecting Rate of Enzyme Reaction a) Temperature b) pH c) Subtrate concentration d) Enzyme Concentration VII. Clinical significance of enzymes Powerpoint Presentation Quiz Assignment : Advance reading for Enzymes Alkaline phosphatase, Alanine aminotransferase, Aspartate aminotransferase

DIPOLOG MEDICAL CENTER COLLEGE FOUNDATION ALLIED MEDICAL SCIENCES MEDICAL TECHNOLOGY DEPARTMENT FIRST SEMESTER SY 2018-2019

PERIOD TOPIC : ENZYMES A. Enzymatic Reaction i. First-order kinetics ii. Zero-order kinetics B. Alkaline phosphatase (ALP) i. Function and Importance of ALP in the body ii. Normal and Abnormal Isoenzymes of ALP iii. Methods that measure ALP iv. Specimen consideration for ALP samples v. Conditions related to High or Low levels of ALP C. Acid phosphatase (ACP) i. Function and Importance of ACP in the body ii. Methods that measure ACP iii. Specimen consideration for ACP samples iv. Conditions related to High or Low levels of ACP D. Alanine aminotransferase (ALT) i. Function and Importance of in the body ii. Normal and Abnormal Isoenzymes of ALT iii. Methods that measure ALT iv. Specimen consideration for ALT samples v. Conditions related to High or Low levels of ALT E. Aspartate aminotransferase (AST) i. Function and Importance of AST in the body ii. Normal and Abnormal Isoenzymes of AST iii. Methods that measure AST iv. Specimen consideration for AST samples v. Conditions related to High or Low levels of AST

F. Lactate dehydrogenase (LD) i. Function and Importance of LD in the body ii. Normal and Abnormal Isoenzymes of LD iii. Methods that measure LD iv. Specimen consideration for LD samples v. Conditions related to High or Low levels of LD Powerpoint Presentation Quiz Advance reading for Cardiac and Pancreatic Enzymes and Pseudocholinesterase

DIPOLOG MEDICAL CENTER COLLEGE FOUNDATION ALLIED MEDICAL SCIENCES MEDICAL TECHNOLOGY DEPARTMENT FIRST SEMESTER SY 2018-2019

PERIOD TOPIC : ENZYMES A. Pseudocholinesterase B. Cardiac Enzymes i. LD ii. Creatine kinase a) Diagnostic significance b) Creatine kinase isoenzymes c) Specimen consideration d) Method to measure Creatine kinase iii. Myoglobin iv. Troponin C. Acute pancreatitis Enzymes i. Amylase a) Diagnostic significance b) Amylase isoenzymes c) Specimen consideration d) Method to measure Amylase ii. Lipase a) Diagnostic significance b) Lipase isoenzymes c) Specimen consideration d) Method to measure Lipase D. Prostatic Cancer Enzymes i. ACP ii. PSA Powerpoint Presentation Quiz Advance reading for Other enzymes

DIPOLOG MEDICAL CENTER COLLEGE FOUNDATION ALLIED MEDICAL SCIENCES MEDICAL TECHNOLOGY DEPARTMENT FIRST SEMESTER SY 2018-2019 PERIOD TOPIC : ENZYMES A. Aldolase i. Diagnostic significance ii. Specimen consideration iii. Method to measure Aldolase B. Leucine Aminopeptidase (LAP) i. Diagnostic significance ii. Specimen consideration iii. Method to measure LAP C. Trypsin i. Diagnostic significance ii. Method to measure trypsin D. 5’ Nucleotidase i. Diagnostic significance ii. Method to measure 5’ Nucleotidase E. Isocitric Dehydrognase i. Diagnostic significance ii. Method to measure Isocitric Dehydrognase F. Sorbitol Dehydrogenase i. Diagnostic significance ii. Method to measure Sorbitol Dehydrogenase G. G 6 PD i. Diagnostic significance ii. Method to measure G 6 PD H. Ornithine Carbamoyl Transferase i. Diagnostic significance ii. Method to measure Ornithine Carbamoyl Transferase Powerpoint Presentation Chapter exam for the whole topic of enzymes Advance reading for Electrolytes

DIPOLOG MEDICAL CENTER COLLEGE FOUNDATION ALLIED MEDICAL SCIENCES MEDICAL TECHNOLOGY DEPARTMENT FIRST SEMESTER SY 2018-2019 PERIOD TOPIC : ELECTROLYTES A. Introduction to Electrolytes a. Discussion about Anions and Cations b. Water content of the body i. Extracellular Fluid (ECF) ii. Intracellular Fluid (ICF) iii. Interstitial Fluid c. Normal Plasma Composition B. Definition of terms a. Osmosis b. Osmotic pressure c. Osmolality C. Importance of Electrolytes in the Body’s processes D. Maintenance of Ion in the plasma or regulation of body fluid compartments E. Importance of Osmolality F. Regulation of Blood Volume

Word Presentation Quiz Advance reading for the electrolyte Sodium

DIPOLOG MEDICAL CENTER COLLEGE FOUNDATION ALLIED MEDICAL SCIENCES MEDICAL TECHNOLOGY DEPARTMENT FIRST SEMESTER SY 2018-2019 PERIOD TOPIC : ELECTROLYTES A. Sodium (Na) i. Clinical significance of Sodium (Na) ii. Processes that determine the plasma Na concentration iii. Clinical Application of Na a) Normal Value Range b) Hyponatremia a. Increased Na loss in the urine b. Increased water retention or water imbalance i. Renal failure ii. Nephrotic syndrome iii. Hepatic cirrhosis iv. Congestive heart failure v. Excess water intake vi. Pseudohyponatremia vii. Syndrome of Inappropriate ADH secretion c) Hypernatremia i. K iv. Determination of Na a) Specimen Consideration b) Laboratory Methods

Word Presentation Quiz Advance reading for the electrolyte Potassium, Chloride, Calcium

DIPOLOG MEDICAL CENTER COLLEGE FOUNDATION ALLIED MEDICAL SCIENCES MEDICAL TECHNOLOGY DEPARTMENT FIRST SEMESTER SY 2018-2019 PERIOD TOPIC : ELECTROLYTES A. Potassium (K) a. Clinical Significance of K b. Reference Values i. Serum ii. Plasma iii. Sweat iv. Urine c. Absorption/Excretion of K in the kidneys d. Function of K e. Hyperkalemia i. Conditions related to Hyperkalemia f.

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