Jurnal 2-wps Office.doc

Jurnal 2 Penulis : Marcella Franquesa , Georgina Pujol-Busquets, Elena García-Fernández , Laura Rico , Laia Shamirian-Pulido , Alicia Aguilar-Martínez , Francesc Xavier Medina, Lluís Serra-Majem and Anna BachFaig Tahun : 2019 Judul : Mediterranean Diet and Cardiodiabesity: A Systematic Review through Evidence-Based Answers to Key Clinical Questions

Sumber (Nama Jurnal atau Prosidings) : pub med (https://www.ncbi.nlm.nih.gov/m/pubmed/30889891/?i=18&from=diabetes mellitus diet) Tujuan Penelitian : The aim of this study was to answer a number of key clinical questions (CQs) about the role of the MedDiet in cardiodiabesity in order to provide a framework for the development of clinical practice guidelines. A systematic review was conducted to answer five CQs formulated using the Patient, Intervention, Comparison, and Outcome (PICO) criteria Hypothesis : There is moderate evidence that MedDiet plays a primary and secondary role in the debate over type 2 diabetes mellitus (T2DM). MedDiet is effective in preventing obesity and MetS in healthy and noisy individuals Metode Penelitian, Material, and Disain Eksperimen : Materials and Methods Literature Search A thorough search of prospective cohort, cross-sectional, and clinical trial studies in the scientific literature was conducted to gather evidence on the ability of the MedDiet to modulate or prevent diseases encompassed by the term cardiodiabesity. Using the same search strategies as GarcíaFernández et al. [6], the available evidence on the association between the MedDiet and cardiodiabesity was updated by reviewing studies published between September 2013 and July 2016. The literature search was performed in PubMed using the search term Mediterranean Diet and the key words Diabetes Mellitus, Coronary Disease, Myocardial Ischemia, Heart Disease, Metabolic Syndrome, and Obesity. Data/ Hasil : Results The new search retrieved 318 articles, of which 186 were excluded on screening the title. Of the remaining 132 articles, 69 were excluded after reading the abstract, and 43 after reading the full text, leaving 20 articles: Five on MetS, five on obesity, three on T2DM, and seven on CVD (Figure 2). Thus, the total number of articles included in the current review was 50: 30 from the original review and 20 from the updated one. Of these, 12 were on MetS, 14 on obesity, seven on T2DM, and 17 on CVD (Table 4 and Table 5). The five CQs were addressed based on different levels of scientific evidence. The level of evidence for each question is shown below, together with the corresponding rationale. Kesimpulan/Diskusi : Conclusions

Recent scientific evidence has shown that the MedDiet, which is listed as a UNESCO (United Nations Educational, Scientific and Cultural Organization) Intangible Cultural Heritage of Humanity [81,82] and referred to in the 2015–2020 American dietary guidelines [83] as an example of a healthy eating pattern, has a beneficial effect on health and sustainability. It also has an important social component [84,85]. The scientific basis for developing evidence-based CPGs consistent with international standards, such as those promoted by the Scottish Intercollegiate Guidelines Network (SIGN) and the United Kingdom’s National Institute for Health and Care Excellence (NICE), has been provided. The reviewed studies show strong evidence of an association between MedDiet adherence and outcomes in cardiodiabesity, which encompasses CVD, T2DM, MetS, and obesity. The MedDiet plays a role in obesity and MetS prevention in healthy or at-risk individuals, and in mortality risk reduction in overweight or obese individuals. Furthermore, it decreases the incidence of T2DM and CVD in healthy individuals, and reduces the severity of symptoms in individuals that already have those diseases. The scientific evidence seems to support the conclusion that MedDiet adherence is a preventive and therapeutic tool for cardiodiabesity.

Abtrak indo Diet Mediterania (MedDiet) telah dipromosikan sebagai cara untuk mencegah dan mengobati kardiodiabesitas. Tujuan dari penelitian ini adalah untuk menjawab sejumlah pertanyaan klinis kunci (CQs) tentang peran MedDiet dalam kardiodiabesitas untuk memberikan kerangka kerja bagi pengembangan pedoman praktik klinis. Tinjauan sistematis dilakukan untuk menjawab lima CQ yang dirumuskan menggunakan kriteria Pasien, Intervensi, Perbandingan, dan Hasil (PICO). Dua puluh artikel yang diterbitkan antara September 2013 dan Juli 2016 dimasukkan, menambah 37 artikel dari ulasan sebelumnya. Ada bukti tingkat tinggi yang menunjukkan bahwa kepatuhan MedDiet berperan dalam pencegahan primer dan sekunder penyakit kardiovaskular (CVD) dan meningkatkan kesehatan pada pasien kelebihan berat badan dan obesitas. Ada bukti sedang hingga tinggi bahwa MedDiet mencegah peningkatan berat badan dan lingkar pinggang pada individu yang tidak gemuk, dan meningkatkan sindrom metabolik (MetS) dan mengurangi insidensinya. Akhirnya, ada bukti moderat bahwa MedDiet memainkan peran primer dan sekunder dalam pencegahan diabetes mellitus tipe 2 (T2DM). MedDiet efektif dalam mencegah obesitas dan MetS pada individu yang sehat dan berisiko, dalam mengurangi risiko kematian pada individu yang kelebihan berat badan atau obesitas, dalam mengurangi kejadian T2DM dan CVD pada individu yang sehat, dan dalam mengurangi keparahan gejala pada individu dengan T2DM atau CVD. .

Jurnal 4 Penulis : D.A. Díaz-Rizzoloa, B. Kostovb, M. López-Silesc, A. Serraa, C. Colungob, L. González-de-Pazb, M. Martinez-Medinac, A. Sisó-Almirallb,d, R. Gomis Tahun : 2019

Judul : Healthy dietary pattern and their corresponding gut microbiota profile are linked to a lower risk of type 2 diabetes, independent of the presence of obesity Sumber (Nama Jurnal atau Prosidings) : pub med (https://www.ncbi.nlm.nih.gov/m/pubmed/30876826/?i=37&from=methods dietary of diabetes) Tujuan Penelitian : The objective of our study, thus, was to understand the impact of dietary patterns on T2D risk as related to gut microbiota profile in obese and non-obese elderly prediabetic subjects. Hypothesis : Metode Penelitian, Material, and Disain Eksperimen : A cross-sectional study was performed in 182 subjects ≥65 years old with prediabetes, divided into obese (OB) or non-obese (NOB) subgroups, and their risk of developing T2D was measured according to FINDRISK score and biochemical parameters. Also, clusters into different dietary patterns in each group by PCA analysis was related with gut microbiota, which was analyzed from stool samples by qPCR. The creation of clusters was used to reevaluate T2D risk. Data/ Hasil : OB was at higher risk of developing T2D and showed worse metabolic outcomes. Unhealthier and healthier dietary pattern clusters were observed for both OB (OB-6 and OB-5 respectively) and NOB (NOB-2 and NOB-3 respectively) groups. Results obtained from the gut microbiota showed that only Prevotella was higher in NOB, but when comparisons were made between clusters, a clear relation with dietary pattern was observed; showing in healthier dietary clusters a decrease in Prevotella, an increase of Faecalibacterium prausnitzii and an increase in lactic acid bacteria. T2D risk was greater in the obese group between unhealthier dietary clusters. No difference between healthier dietary clusters was observed. Kesimpulan/Diskusi A healthy dietary pattern and the growth-promoting beneficial and growth-inhibiting disadvantageous gut microbiota populations linked to it provide protection against the development of T2D in an obese population with advanced age and preDM.