Immunologic Deficiency Syndromes

IMMUNOLOGIC DEFICIENCY SYNDROMES R. HUGO MARTÍNEZ LOZANO, M.D. Sep-14, 2006

IMMUNOLOGIC DEFICIENCY SYNDROMES. I.- LEARNING OBJECTIVES: A.- IMMUNE RESPONSE AND INFECTIONS B.- IMMUNE DEFICIENCIES: TYPES: 1.- PRIMARY - ETIOLOGY - PATHOGENESIS - CHARACTERISTICS - RECOMMENDED STUDY - CLINICAL SIGNIFICANCE!!

IMMUNE DEFICIENCY SYNDROMES. I.- LEARNING OBJECTIVES: 2.- ACQUIRED: - CAUSES: -AGING -MEDICINE -CANCER -MALNUTRITION -AIDS -INFECTIONS -NEOPLASIA - MORPHOLOGY - CLINICAL SIGNIFICANCE!! REF: pp. 240-258

MECHANISMS OF IMMUNITY

IMMUNE DEFICIENCY SYNDROMES. II.- PRIMARY: - CHARACTERISTICS. - COMMON INHERITANCE - SPECIFIC VS NONSPECIFIC - TYPES ON INFECTION

PATHOGENESIS OF PRIMARY IMMUNEDEF.

IMMUNE DEFICIENCY SYNDROMES. II.- PRIMARY: RECOMMENDED STUDY: - X-LINKED AGAMMAGLOBULINEMIA - COMMON VARIABLE IMMUNODEF. - ISOLATED IgA DEF. - DiGEORGE SYNDROME - SEVERE COMBINED IMMUNODEF.

GIARDIA LAMBLIA

IDEM

COMMON VARIABLE IMMUNODEFICIENCY DIFFERENCES (W/BRUTON’S): - GENDER - Ig LEVELS - PERIPHERAL B CELLS - CLINICAL – HERPES INF. - AUTOIMMUNE DIS. - MALIGNANCIES

ISOLATED IgA DEFICIENCY DIFFERENCES (W/BRUTON’S): - EPIDEMIOLOGY - Ig TYPES - Ab VS IgA - GENDER, PERIPHERAL B CELLS, AUTOIMMUNE DIS.

SCID SPECTRUM OF DIFFERENT DISEASES - X-LINKED –R FOR IL - AR –ADA DEF. - OTHER. PROFOUND DEFECTS – HUMORAL - CELLULAR 

“ASPERGILLOMA”

PNEUMOCYSTOSIS

HISTOPLASMOSIS (LIVER)

IDEM: (KENYOUN STAIN)