Hershey & Chase Worksheet

  • April 2020
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YOUR TURN! You are given a section of your very own textbook, just as I was. Instead of just reading it- how boring- WRITE a story to go along with it, as I did. Make it dramatic. Make it shine. You may draw pictures if you wish, to help the other group! ALSO write the MAIN POINT of BOTH stories below the story that you are given; and after you hear the other story. STAPLE YOUR OWN STORY TO THIS SHEET!! The story of Hershey and Chase (excerpt from book) Main point:

One kind of virus that infects and kills bacteria is known as a bacteriophage (bak-TEER-ee-uh-fayj), which means, “bacteria eater”. Bacteriophages are comprised of a DNA or RNA core and a protein coat. When a bacteriophage enters a bacterium, the virus attaches to the surface of the cell and injects its DNA into it. The viral genes act to produce many new bacteriophages, and they gradually destroy the bacterium. When the cell splits open, hundreds of new viruses burst out. Hershey and Chase reasoned that if they could determine which part of the virus- the protein coat or the DNA core- entered the infected cell, they would learn whether genes were made of protein or DNA. To do this, the grew viruses in cultures containing radioactive isotopes of phosphorus-32 and sulfur-35. This was a clever strategy because proteins contain almost no phosphorus and DNA contains no sulfur. The radioactive substances could be used as markers. If S-35 was found in the bacteria, it would mean that the virus’ protein had been injected into the bacteria. If P- 32 was found in the bacteria, then it was the DNA that had been injected. The Hershey-Chase experiment is shown on the powerpoint. The two scientists mixed the marked viruses with bacteria. Then, they waited a few minutes for the viruses to inject their genetic material. Next, they separated the viruses from the bacteria and tested the bacteria for radioactivity. Nearly all the radioactivity in the bacteria was from the phosphorus (P-32), the marker found in DNA. Hershey and Chase concluded that the genetic material of the bacteriophage they infected with bacteria was DNA, not protein. This Avery and that DNA Main point:

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