GENETIC ENGINEERING By SADIQ HASAN BUKAI FA06-BB-0083
AGENDA 1. HISTORY OF GENETIC ENGINEERING 2. WHAT IS GENETIC ENGINEERING 3. WHAT IS A D.N.A 4. PROCESS OF GENETIC ENGINEERING 5. APPLICATION OF GENETIC ENGINEERING 6. WHAT ARE THE DANGERS 7. CONCLUSION
HISTORY OF GENETIC ENGINEERING • THE TERM “GENETIC ENGINEERING” WAS COINED IN JACK WILLIAMSON’S SCIENCE FICTION NOVEL DRAGON ISLAND PUBLISHED IN 1951. • TWO YEARS BEFORE JAMES WATSON & FRANCIS CRICK SHOWED THAT D.N.A COULD BE A MEDIUM OF TRANSMISSION OF GENETIC INFORMATION.
WHAT IS GENETIC ENGINEERING?
Genetic Engineering is a laboratory technique used by scientist to change the D.N.A of living organisms.
WHAT IS A D.N.A?
D.N.A is a blue print for the individuality of an organism.
WHAT IS GENETIC ENGINEERING? • Molecular Biologist discovered enzymes which change the structure of D.N.A in living organism. • Scientist learned about vectors, strands of D.N.A such as viruses • Building vectors to incorporate in the Genes. • Genetic engineering is different from traditional breeding.
PROCESS OF GENETIC ENGINEERING 1. ISOLATION OF THE GENES OF INTEREST 2. INSERTION OF THE GENES INTO A TRANSFER VECTOR. 3. TRANSFER OF THE VECTOR TO THE ORGANISM TO BE MODIFIED 4. TRANSFORMATION OF THE CELLS OF THE ORGRANISM 5. SELECTION OF GMO FROM THOSE THAT HAVE NOT BEEN SUCCESSFULLY MODIFIED.
APPLICATION OF GENETIC ENGINEERING • IMPROVING CROP TECHNOLOGY • MANUFACTURE OF SYNTHETIC HUMAN INSULIN. • NEW TYPE OF EXPERIMENTAL MICE SUCH AS OHCOMOUSE (CANCER MOUSE) • 1987 FDA (FOOD & DRUG ADMIN) APPROVED FIRST GENETICALLY ENGINEERED VACCINE FOR HEPATITIS B.
WHAT ARE THE DANGERS • IMPRECISE TECHNOLOGY: (1998) Gene cut precisely from the DNA of an organism but insertion is basically random. Consequences is there is a risk that it may disrupt the functioning of other gene essential to the life of that organism.
WHAT ARE THE DANGERS • SIDE EFFECTS (1998) Scientist do not understand living system completely enough to perform DNA surgery. Harmful to the environment and our health. • WIDE SPREAD CROP FAILURE (1996) When a farmer plants genetically engineered seeds. There could be a widespread crop failure.
WHAT ARE THE DANGERS • Threatens our entire food supply • No long term safety testing • Toxins • Allergic reaction • Problems cannot be traced.
CONCLUSION
GENETIC ENGINEERING IS LIKE PERFORMING HEART SURGERY WITH A SHOVEL.
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