Female Reproductive Cycle

1) FSH + LH ↑ 2) Multiple early antral follicles grow and make E 3) Serum E ↑ 4) One follicle becomes dominant 5) Serum E ↑↑↑ 6) FSH ↓ due to (-) feedback of E + INH 7) E feedback switches from (-) to (+) 8) LH surge is triggered 9) Oocyte completes 1st meiotic division 10) Ovulation occurs 11) CL forms and makes P and some E 12) Serum P ↑↑↑ INH ↑ 13) FSH and LH are inhibited 14) CL begins to regress (cause unknown) 15) Serum P and E fall 16) FSH + LH ↑