Establishment Of Vascular System

Establishment of the Vascular System

3 Principal Mechanisms • Vasculogenesis – the process of blood vessel formation by production of endothelial cells

• Angiogenesis – denotes the formation of new blood vessels from pre-existing ones

• Invasion of existing vascular buds by migrating angioblasts

Angiogenesis • Sprouting angiogenesis – forms entirely new vessels from pre-existing ones

• Intussusceptive angiogenesis – also known as splitting angiogenesis wherein the capillary wall extends into the lumen to split a single vessel in two. – important because it is a reorganization of existing cells – allows a vast increase in the number of capillaries without a corresponding increase in the number of endothelial cells.