Anggita Nur F Kimfis 2.docx

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Diah Ardiana (1408010071) Kelas C K degredasi pada suhu 35C C0 - C = Y 0,00 0,38 0,59 0,99 1,31 1,78

C - Co 0,00 -0,38 -0,59 -0,99 -1,31 -1,78

Slope = b = k

0,01995

-0,01995

linaritas = r

0,99209

0,992086

0,00009548 0,99223

intersep = a

0,04357

-0,04357

0,000203104

Kons Obat (M) 209,89 209,51 209,3 208,9 208,58 208,11

Waktu (X) 0 15 30 45 60 90

Waktu (X) 0 15 30 45 60 90

ln Co/C 0 0,00181 0,00281 0,00473 0,00626 0,00852

t1/2 = 0,693/k t90% = 0,105/k

Waktu (X) 0 15 30 45 60 90

ln C/Co 0 -0,00181 -0,00281 -0,00473 -0,00626 -0,00852 (0,00009548) 0,99223 0,000203104

7258,418324 -1099,760352

GRAFIK KOSENTRASI VS WAKTU

GRAFIK LN C/Co VS WAKTU 0 -0.002

210

Ln C/Co

Kosentrasi (M)

Co C dst

Waktu (X) 0 15 30 45 60 90

209 208 0

20

40

60 Waktu

80

100

0

20

40

60

-0.004 -0.006 -0.008 -0.01

Waktu

80

100

K degredasi pada suhu 45C Kons Obat (M) 209,89 209,48 209,33 208,86 208,54 207,94

Waktu (X) 0 15 30 45 60 90

C0 - C = Y 0 0,41 0,56 1,03 1,35 1,95 0,02168 0,99228 0,01629

C - Co 0 -0,41 -0,56 -1,03 -1,35 -1,95 -0,02168 0,99228 -0,01629

Waktu (X) 0 15 30 45 60 90

GRAFIK KONSENTRASI VS WAKTU

ln Co/C 0 0,001955 0,002672 0,004919 0,006453 0,009334 0,00010376 0,992327 7,16842E-05 6678,72028 1011,927315

Waktu (X) 0 15 30 45 60 90

ln C/Co 0 -0,001955315 -0,00267163 -0,004919413 -0,006452715 -0,009334007 -0,000103762 0,992327 -7,16842E-05

GRAFIK Ln C/Co VS WAKTU 0

210

-0.002

209

Ln C/Co

Kosentrasi (M)

Co C dst

Waktu (X) 0 15 30 45 60 90 Slope = b = k linaritas = r intersep = a t1/2 = 0,693/k t90% = 0,105/k

208 207 0

20

40

60 Waktu

80

100

0

20

40

60

-0.004 -0.006 -0.008 -0.01

Waktu

80

100

Energi Aktivasi pada suhu 35C dan 45C t 25

T 298

1/T 0,00336

35

308

0,00325

45

318

0,00314

k

0,00009548 0,000103762

ln K -9,2566425 -9,17340695

ln (K35-K45)

ln (k35/K45)

1/T45 - 1/T35

Ea

-0,083235549

-0,08323555

-0,000102099

6777,924186

t 25

T 298

1/T 0,00336

t1

35

308

0,00325

t2

45

318

0,00314

K

lnK

0,00009548 0,000103762

-9,2566425

ln (K35-K45)

ln (K35/K45)

1/T45 - 1/T35

Ea

-0,083235549

-0,08323555

-0,000102099

6799,9357

anti ln

k25

-9,17340695

Mencari K pada suhu 25 t

T

1/T

t1

25

298

0,003356

t2

35

308

0,003247

Usia simpan (T90%) t90 = 0,105/k t 90 pada 25 der C = 1202,26 Bulan 100,1883 Tahun

1/T25 - 1/T35

ln (k35/k25) = …

0,000108951

0,089

ln (0.000095475345/k35) = 0.089 1n (0.000095475345/K25) = 0,089

1,093201208

0,00008734

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