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Brand Name: Anestacon, Dermaflex Generic Name: Lidocaine Indications: Cardiac arrythmias, Ventricular ectopy, ventricular tachycardia, Ventricular fibrillation Drug Classification: Local Anesthetic Mechanism of Action: Class IB antiarrhythmic; suppresses automaticity of conduction tissue, by increasing electrical stimulation threshold of ventricle, HIS-Purkinje system, and spontaneous depolarization of the ventricles during diastole by a direct action on the tissues; blocks both the initiation and conduction of nerve impulses by decreasing the neuronal membrane’s permeability to sodium ions, which results in inhibition of depolarization with resultant blockade of conduction Dosage: Adult: not more than 200-300 mg lidocaine administered during a 1-hr period. Children 30 mcg/kg/min by infusion, following appropriate bolus administration (1 mg/kg). Special Precaution: Renal, cardiac or hepatic failure; sinus bradycardia; diabetes mellitus; digitalis toxicity w/ AV block. Pregnancy Risk Category: B (per manufacturer);C (based on expert analysis)

Adverse Reactions: CV: Hypotension. CNS: Positional headache. Miscellaneous: Shivering Contraindications:  Known hypersensitivity to amide-type local anesthetics  Patients with Adams-Stoke syndrome or with severe degree of S-A, A-V  Intraventricular heart block (without a pacemaker) Form: INJ – 1g/250 mL Nursing Responsibilities:  Monitor fluid balance  Assess IV site  Monitor blood pressure, heart rate & pulse